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Sildenafil is a medication used to treat erectile dysfunction in men (also called sexual impotence). Sildenafil belongs to a class of drugs known as phosphodiesterase 5 (PDE5) inhibitors. These medications stop an enzyme known as phosphodiesterase type-5 from working too quickly. This enzyme works in the penis, among other places.
Erectile dysfunction occurs when a man's penis does not harden and expand when sexually excited, or when he is unable to maintain an erection. When a man is sexually stimulated, his body's natl reaction is to increase blood flow to his penis in order to produce an erection. Sildenafil helps to maintain an erection after the penis is stroked by controlling the enzyme. Sildenafil will not work to cause an erection unless there is physical action to the penis, such as during sexual intercourse. Sildenafil is also used to treat the symptoms of pulmonary arterial hypertension in both men and women.
This is a form of hypertension that occurs between the heart and the lungs. When pulmonary hypertension occurs, the heart must work harder to pump enough blood through the lungs. Sildenafil relaxes blood vessels by acting on the PDE5 enzyme in the lungs.
This increases the supply of blood to the lungs while decreasing the workload on the heart. Inform your doctor if you have ever experienced an unusual or allergic reaction to this or any other medications. Inform your doctor if you have any other allergies, such as those to foods, dyes, preservatives, or animals. When purchasing non-prescription products, carefully read the label or package ingredients. Sildenafil should never be used to treat erectile dysfunction in children. In general, sildenafil should not be used in children, especially for chronic pulmonary arterial hypertension.