SARS-CoV-2 Spike-pseudovirus Based Neutralization Assay

[Sherwinbrown]

The SARS-CoV-2 spike pseudovirus is a valuable tool in the study of COVID-19, particularly in understanding the virus's ability to infect human cells. By using a pseudovirus that mimics the spike protein of SARS-CoV-2, researchers can assess the effectiveness of vaccines, therapeutics, and neutralizing antibodies in a controlled laboratory setting. The SARS-CoV-2 spike pseudovirus system allows for safer, high-throughput screening of potential treatments, offering critical insights into how the virus interacts with host cells. This approach has been instrumental in advancing our understanding of viral entry mechanisms and the immune response to COVID-19.